icon-nav-help
Need Help

Submit your question to our team of health care professionals.

icon-nav-current-questions
Current Question

See what's on the mind of the community right now.

icon-conf-speakers-at-a-glance
Meet the Team

Learn more about our world-renowned team.

icon-nav-archives
CWD Answers Archives

Review the entire archive according to the date it was posted.

CWD_Answers_Icon
February 14, 2006

Research: Causes and Prevention

advertisement
Question from Rockaway, New Jersey, USA:

Is there any evidence that the taking of common antidepressants by pregnant women increase the chances of the child getting type 1 diabetes? I have read that schizophrenia medications can cause diabetes for the user.

Answer:

From: DTeam Staff

I did a medline search and could not find any specific reference to prenatal use of antidepressants and the baby developing diabetes. There is a recent review (Expert Opinion Drug Safety, January 2006) that states that certain types of antidepressants can affect glucose metabolism. The class known as SSRIs (Prozac) may reduce hyperglycemia whereas the heterocyclics (Norpramin) may cause the opposite. Whether this has any long term effect on glucose metabolism in a fetus is unknown. Of some concern is a recent New England Journal report that SSRIs may be associated with pulmonary hypertension in the newborn.

OWJ
Additional comments from Dr. Stuart Brink:

Nope. Modern SSRI medications can elevate blood glucose levels sometimes, but it is difficult to know exactly how this occurs. It could be insulin resistance, could be direct insult on the pancreas, etc. There are a lot of theories but no hard evidence. Whether or not the same might happen with pregnancy is even less known, but probably also less likely. You should discus this with your psychiatrist and perhaps also with your obstetrician. If you still have some questions, a consultation with a diabetologist would be reasonable.

SB