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November 12, 2001

Other Illnesses

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Question from Wakefield, Rhode Island, USA:

What can you tell me about non-alcoholic steatohepatitis?

Answer:

From: DTeam Staff

It is a form of fatty degeneration of the liver often associated with type 2 diabetes, obesity and insulin resistance. It has been reported in a child as a very rare occurrence. There is a good summary in Diehl, AM. Nonalcoholic steatohepatitis Semin Liver Dis 1999;19(2):221-9.

DOB
Additional comments from Dr. Stuart Brink:

Nonalcoholic steatohepatitis is usually associated with obesity, and lipid abnormalities. It is sometimes seen in type 2 adults and kids. This same group would also be prone to develop classical type 2 diabetes. Liver enzymes are often mildly elevated. Weight loss helps. lipid medications sometimes help as do all the oral hypoglycemic agents to control glycemia. We are seeing more and more of these problems because of the obesity epidemic in this country and all around the world.

SB

[Editor’s comment: Nonalcoholic steatohepatitis is sometimes referred to by its acronym, NASH.

WWQ]