
April 23, 2001
Research: Causes and Prevention
Question from McCleary, Washington, USA:
I recently got put on NPH and Regular insulin shots twice a day, because my doctor is trying to see if taking insulin will possibly prevent type 2 diabetes in me. Is this possible?
Answer:
I know of no research into prevention of type�2 diabetes by giving insulin. I do know that there is a project of the NIH, the Diabetes Prevention Trial for Type 1 or DPT-1 trial, in which insulin is the specific intervention.
For type 2, the Diabetes Prevention Program (at the Diabetes Monitor). intervenes with diet, exercise, and, for some, the drug Glucophage [metformin]. So, I can’t answer the first question based on any research. I have given the research as I know it. You might ask whether your doctor is thinking of type�1 or type 2. If your doctor is thinking of type 1, has he looked at islet cell antibodies, etc? These are increased in those predisposed to type 1 diabetes a lot of the time. For type 2, has he looked at C-peptide, a measure of insulin secretion? That might be helpful.
LD