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Insulin

My 6 year old daughter has been diabetic for 3 years and is currently taking part in a trial for a new insulin called Biphasic Aspart. I am having trouble locating any studies or reports on the trials which have already been carried out on adults worldwide for this insulin – can anyone help?

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My brother-in-law has had type 1 diabetes for 24 years. He used beef/pork insulin for 23 years and never had problems with hypoglycemia. His doctor changed him to human insulin (Reg/NPH) last year. Since then he has had many lows and has started to develop unawareness. What is different about the human insulin?

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On my last two visits, two separate consultants have said my daily intake of insulin (90 to 100 units per day) is more than a normal person produces. What if any, are the dangers or consequences of this in the long run?

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What are your thoughts on the new insulin, glargine, just approved by the FDA? Will it replace the need for the pump?

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How do insulin and the body react with other drugs?

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Can you have side effects from certain kinds of insulin?

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I am on Insulatard [NPH] and Actrapid [Regular] and have recently asked to be put on Lantus. I am waiting to see my diabetes nurse about starting it. She is keen that I stay on Actrapid to cover the bolus, rather switch to a shorter lasting insulin. Given that Actrapid lasts 4-5 hours, do you think Humalog would be more appropriate?

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I work at an institution for the developmentally disabled, and there are not many people with diabetes here, but we have recently gotten a 20 year old woman with newly diagnosed type 1 diabetes, and the physicians are a little rusty on prescribing dosages. The only insulin regimen they are using is Regular and NPH. How do we calculate an insulin dose?

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My son is a college student. Two years ago, as a high school senior, we tried him on Lantus and Humalog. He developed a very low heart rate and very low blood pressure. After many tests we finally insisted it was the insulin and put him back on regular and NPH. He got better. He wishes for a more flexible mix.

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I have been on NPH and Regular insulin for 12 years, I am very well controlled, and I visit the doctor three times a year for the routine blood work and review of my insulins. How comparable is one insulin brand to another? Is is safe to change insulin brands?

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