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Genetics and Heredity

My two year old son was diagnosed with type 1 diabetes six months ago, and while neither my husband nor I have a family history of diabetes, but my husband has had celiac disease since he was a baby. Is there a link between my husband’s celiac disease and my son’s diagnosis? Is my son at higher risk for developing celiac disease than other people with type 1 diabetes?

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My almost eight year old son has had type 1 diabetes since the age of four, and my 11 year old daughter was recently (within the past three months) diagnosed. How common is it for siblings to have type 1 diabetes with no family history of the disease?

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I realize that there is some genetic component to type 1 diabetes, but I’m surprised that so many family members have now been diagnosed. Is this unusual?

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I have had type 1 diabetes for 13 years. My girlfriend also has it. What are the consequences for our marriage?

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Are there any particular groups that are more likely to have diabetes than any others?

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I have been experiencing dizziness, headaches, nausea and numbness on the left side of my body only. I am going to be tested for diabetes, which runs in my father’s family. I am also overweight. Is diabetes hereditary?

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What are the odds of one family having three children with diabetes? Could my children have type 1 due to their father’s family having rheumatoid arthritis?

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Both my husband and older son have type 1. Our infant son doesn’t have the high risk genes. Is there still a higher probability than the general population that he might get type 1?

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My five year old adopted son was diagnosed with transient neonatal diabetes at one month of age. Two months ago, when he was placed with us for adoption, a routine physical showed high blood sugar levels. He tested negative for antibodies. The doctor feels that he has uniparental bisomy of chromosome 6.

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What type of mutation (i.e., frameshift, point, chromosomal, and disjunction) is diabetes? Is it different for type 1 and type 2?

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